Leona & Zeri vs Samira & Milio
Bot Lane Matchup
You
VS
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Who Wins
- Pre-6 you have strong engage advantage with E-Q combo that they struggle to answer cleanly.
- Post-6 becomes more difficult as Milio R cleanses your CC and provides healing, making your all-ins less reliable without perfect execution.
Synergy & Trading
- Look for E-Q combos when Milio is positioned poorly or has used Q, then follow with W for extended trades.
- Your R provides excellent follow-up engage after initial combo, especially if you can catch multiple targets or force Milio's cleanse early.
Wave Control/Roaming
- Roam frequently after successful trades or when Zeri has lane priority, focusing on mid lane ganks or river control.
- Best timings are when enemies recall or when your ADC can safely farm under tower with minion advantage.
Mistakes to Avoid
- Don't engage when Milio has both W and R available unless you can guarantee a quick kill - his cleanse effects make your CC unreliable.
- Avoid using E without proper minion setup since Samira can dash through creeps to dodge and counter-engage.
Created on 01/18/2026
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