Leona & Kai'Sa vs Miss Fortune & Seraphine
Bot Lane Matchup
You
VS
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Who Wins
- You lose pre-6 due to Miss Fortune's superior poke and Seraphine's sustain negating your all-in attempts.
- Post-6 your R gives better engage potential, but their R abilities (Miss Fortune's damage and Seraphine's charm) make teamfights dangerous.
Synergy & Trading
- Look for E-Q combos when enemies step forward for CS or poke, then immediately W for damage reduction.
- Coordinate with Kai'Sa's W slow to land your abilities more reliably and enable her plasma proc damage.
Wave Control/Roaming
- Roam when the wave is pushing toward enemies and Kai'Sa can farm safely under tower.
- Best timings are after successful recalls or when mid lane is gankable around levels 4-6 before teamfights start.
Mistakes to Avoid
- Don't engage without checking Seraphine's E cooldown, as her root can turn your engage into a death sentence.
- Avoid fighting in minion waves where Miss Fortune's Q bounce and R damage are maximized.
Created on 12/18/2025
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