Karma & Ezreal vs Ashe & Seraphine

Karma
You
Ezreal
VS

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Who Wins

  • Pre-6: Even matchup with slight edge to enemies due to Ashe range and Seraphine sustain, but your R+Q can create picks.
  • Post-6: Ashe+Seraphine wins decisively through superior engage range and guaranteed follow-up damage.

Synergy & Trading

  • Look for R+Q poke when enemies are grouped for CS, then shield Ezreal for his follow-up combo.
  • Use W tether when Seraphine steps up to trade, forcing her to choose between backing off or taking significant damage.

Wave Control/Roaming

  • Yes, roam after shoving waves or when Ezreal can safely farm under tower.
  • Optimal timings are levels 3-5 before Seraphine gets strong waveclear, and after successful recalls when you have R available.

Mistakes to Avoid

  • Don't waste R on shields in neutral trades as you need it for meaningful Q poke or disengage.
  • Never use W defensively on Ezreal when enemies aren't committed, as it removes your only hard CC for picks.
Created on 03/18/2026
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