Kai'Sa & Neeko vs Ziggs & Brand
Bot Lane Matchup
You
VS
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Who Wins
- You lose level 2 fights due to their superior burst and range advantage.
- Level 6 is winnable if Neeko lands E and you can R in safely, but their combined ultimates make extended fights very risky.
Synergy & Trading
- Stay behind minions and only trade when Neeko lands E root for guaranteed W proc.
- Use Q through minions to farm safely and only auto-attack when their abilities are on cooldown.
Wave Control/Roaming
- Farm under tower and look for short trades only when abilities are down.
- Avoid pushing as you'll be exposed to constant poke and have no escape from their zone control.
Mistakes to Avoid
- Don't use R aggressively without knowing where their ultimates are as Brand R plus Ziggs R will kill you instantly.
- Never fight in minion waves where Brand's passive can spread and Ziggs Q can bounce.
Created on 11/22/2025
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