Ezreal & Lux vs Vayne & Alistar

Ezreal
You
Lux
VS
Vayne
Alistar

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Who Wins

  • You win pre-6 through superior range and Lux's Q threat, forcing Vayne into defensive positioning.
  • Post-6 becomes more dangerous as Vayne's R stealth makes her harder to target, but your E and Lux's disengage tools still give you the edge.
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Synergy & Trading

  • Use Q poke when Vayne steps up to last-hit, and coordinate with Lux Q when Alistar positions aggressively.
  • Your best trades involve E forward for W-auto-Q combo when their abilities are down, then E back to safety.

Wave Control/Roaming

  • Push waves with Q to maintain range advantage and prevent Vayne from freezing near her tower.
  • Look for slow pushes that build up minion advantages before backing, as this forces them to choose between losing CS or taking poke.

Mistakes to Avoid

  • Don't E forward aggressively when Alistar has W-Q available, as getting combo'd means taking Vayne's full damage output.
  • Avoid wasting E on damage when you might need it to escape Alistar's engage.
Created on 03/28/2026
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