Cassiopeia vs Annie
Mid Lane Matchup
You
VS
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Who Wins
- You win most early trades with Q-E spam due to your superior range and sustained damage output.
- Post-6, you need to respect Annie's flash-R engage range, but you can still win if you land your R first or dodge hers.
How to Trade
- Your optimal trading pattern is landing Q then following with multiple E casts while kiting backwards.
- Space properly to avoid her W-Q combo while maintaining E pressure, and use W for disengage if she tries to all-in.
Wave Control
- Maintain slow pushes to keep the wave in favorable positions while poking her down with Q-E.
- You can match her waveclear with E spam on minions, but be mindful of your mana costs compared to her more efficient clearing.
Mistakes to Avoid
- Don't waste your R defensively unless you're certain you'll die, as Annie's burst combo can be survived with proper positioning.
- Avoid face-checking bushes when she has passive stacks, as her flash-R range can catch you off-guard.
Created on 12/24/2025
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