Caitlyn & Pyke vs Miss Fortune & Karma

Caitlyn
You
Pyke
VS
Miss Fortune
Karma

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Who Wins

  • You win pre-6 trades due to superior range and Pyke's hook threat, but Miss Fortune's Q bounce damage can chunk you if positioned poorly.
  • Post-6 becomes more even as Miss Fortune's R forces you to respect her all-in potential while your range advantage remains.
Confused by a term? Check the Glossary

Synergy & Trading

  • Use your range to auto-attack when enemies step up for CS, then follow with Q when they're slowed by Karma's tether or hooked by Pyke.
  • Focus on headshot procs on trapped or hooked targets for maximum damage output.

Wave Control/Roaming

  • Push early waves to establish range advantage and trap control around river bushes.
  • Maintain slow pushes to build minion advantages for trades while keeping traps in key positions to zone enemies from CS.

Mistakes to Avoid

  • Don't get caught by Miss Fortune's Q bounce damage by standing behind low-health minions.
  • Avoid face-checking brushes without trap vision as Pyke's hook from fog of war can instantly turn favorable positioning into a death sentence.
Created on 02/27/2026
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