Ashe & Karma vs Caitlyn & Senna
Bot Lane Matchup
You
VS
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Who Wins
- You lose pre-6 2v2s due to Caitlyn's range advantage and headshot trades, while Senna provides sustain and additional poke.
- Post-6 your R engage potential is limited by Caitlyn's E escape and Senna's W root interruption.
Synergy & Trading
- Use W poke when Karma's R+E gives you movement speed to avoid Senna's W root retaliation.
- Your strongest trading windows come after Caitlyn uses Q on minions, allowing you to W+auto before she can headshot trade back.
Wave Control/Roaming
- Look for slow pushes into recalls since you cannot match Caitlyn's freeze control or Senna's sustain in extended laning.
- Use W to maintain last-hit range when they establish freezes, but avoid overextending for farm.
Mistakes to Avoid
- Don't use R aggressively without Karma's R+E speed boost since Caitlyn can easily E away from your arrow.
- Avoid auto-attacking through minions early game as Caitlyn will win every headshot trade with her range advantage.
Created on 01/03/2026
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