Alistar & Caitlyn vs Ezreal & Pyke

Alistar
You
Caitlyn
VS

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Who Wins

  • You win level 2 strongly with W-Q combo setting up Caitlyn's damage and trap follow-up.
  • Level 6 solidifies your advantage as your R provides excellent peel against Pyke's assassination attempts while maintaining engage potential on Ezreal.

Synergy & Trading

  • W-Q combo Ezreal when he steps up for CS or Q poke, immediately followed by Caitlyn's W trap placement for guaranteed follow-up.
  • Use E to heal through Ezreal's poke damage and maintain health for future engage opportunities.

Wave Control/Roaming

  • Roam when Caitlyn has significant wave control and vision advantage, typically after successful recalls or when enemies are low.
  • Best roam timings are post-level 6 when your full combo with R provides guaranteed kill setup for mid lane or jungle skirmishes.

Mistakes to Avoid

  • Don't W forward when Pyke has E available and you're not certain of the kill, as his E displacement can separate you from Caitlyn.
  • Avoid using W-Q combo when low on health without R available, since Pyke's R execute threshold increases significantly with missing health.
Created on 11/20/2025
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